The United Nations delivered 27 truckloads of humanitarian aid to Syria's northwestern Idlib province, local sources said.
The convoy passed through the Cilvegozu border crossing in Turkey's southern Hatay province, said the sources, speaking on condition of anonymity.
The humanitarian aid will be distributed to people in need in Idlib and its rural areas.
Syria has only just begun to emerge from a devastating conflict that began in 2011 when the Bashar al-Assad regime cracked down on demonstrators with unexpected ferocity.
Hundreds of thousands of civilians have been killed or displaced in the conflict, mainly by regime airstrikes targeting opposition-held areas.
Reporting by Cem Genco:Writing by Erdogan Cagatay Zontur